About 12 results found for searched term "51-48-9" (0.055 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3385 | Cimetidine | Histamine Receptor |
| SKF-92334 | ||
| Cimetidine, a histamine congener, competitively inhibits histamine binding to histamine H2 receptors. | ||
| M5137 | BML-277 | Checkpoint |
| Chk2 Inhibitor II | ||
| BML-277 is a high efficient Chk2 inhibitors, IC50 is 15 nM. | ||
| M5758 | L-Thyroxine | Metabolite/Endogenous Metabolite |
| NSC 36397 | ||
| L-Thyroxine is a synthetic form of thyroxine and a hormone replacement compound. | ||
| M6630 | CP 99994 dihydrochloride | Others |
| CP 99994 dihydrochloride is a high affinity NK 1 antagonist. | ||
| M10114 | PMX 205 Trifluoroacetate | Complement System |
| PMX 205 TFA | ||
| PMX 205 Trifluoroacetate is a potent complement antagonist of C5a (C5aR; CD88) receptor. | ||
| M11529 | Temuterkib | ERK |
| LY3214996 | ||
| Temuterkib (LY3214996) is a selective, novel erK1/2 inhibitor with an IC50 of 5 nM against ERK1 and ERK2. It can effectively inhibit intracellular P-RSK1 in cancer cell lines with BRAF and RAS mutations. Temuterkib has strong antitumor activity in cancer models with altered MAPK pathways. | ||
| M14681 | Dehydroepiandrosterone sulfate | Others |
| DHEA sulfate; Prasterone sulfate | ||
| Dehydroepiandrosterone sulfate, a neuroactive neurosteroid, plays a major role in brain development and aging by influencing the migration of neurons, arborization of dendrites, and formation of new synapses. | ||
| M17545 | Vibralactone D | Sesquiterpenoids |
| Vibralactone D is a metabolite isolated and cultured from a naturally occurring ascomycete and exhibits weak inhibitory activity (IC50 85.7 μM) against the isoenzyme of 11b-hydroxysteroid dehydrogenase (HSD). | ||
| M24707 | Indusatumab vedotin | Drug-Linker Conjugates for ADC |
| MLN0264; TAK-264 | ||
| Indusatumab vedotin (MLN-0264; AKT-264) is an antibody-drug conjugate (ADC) consisting of the human anti-guanylate cyclase C (GCC) antibody linked to a microtubule-disruptor Monomethyl auristatin . Indusatumab vedotin has anti-proliferative effects on pancreas cancer cell lines. Indusatumab vedotin arrests cell cycle at G2/M phase, and induces apoptosis. | ||
| M28475 | Piribedil dihydrochloride | Adrenergic Receptor |
| Piribedil dihydrochloride is a potent and orally active dopamine D2 and dopamine D3 agonist. Piribedil dihydrochloride is also a α2-adrenoceptors antagonist. Piribedil dihydrochloride can inhibit MLL1 methyltransferase activity (EC50: 0.18 μM). Piribedil dihydrochloride has the potential for the research of parkinson's disease, circulatory disorders, cancers. | ||
| M30222 | PMX 205 | Complement System |
| PMX 205 is a potent complement C5a receptor (C5aR; CD88) antagonist. | ||
| M44208 | Ampelopsin G | Others |
| Ampelopsin G | ||
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