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ZL-2201

Cat. No. M41474

All AbMole products are for research use only, cannot be used for human consumption.

ZL-2201 Structure

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Quality Control & Documentation
Biological Activity

ZL-2201 is a potent DNA-PK inhibitor with an IC50 of 1 nM.

Chemical Information
Molecular Weight 503.53
Formula C20H25N9O5S
CAS Number 2865115-39-3
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Shruti Lal et al. Cancer Res Commun. Discovery and Characterization of ZL-2201, a Potent, Highly Selective, and Orally Bioavailable Small-molecule DNA-PK Inhibitor

Related DNA-PK Products
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AMA-37 

AMA-37, an Arylmorpholine analog, is ATP-competitive DNA-PK inhibitor, with IC50 values of 0.27 μM (DNA-PK), 32 μM (p110α), 3.7 μM (p110β), and 22 μM (p110γ), respectively.

PIK-75 

PIK-75 is a reversible DNA-PK and p110α-selective inhibitor, which inhibits DNA-PK, p110α and p110γ with IC50s of 2, 5.8 and 76 nM, respectively. PIK-75 inhibits p110α >200-fold more potently than p110β (IC50=1.3 μM). PIK-75 induces apoptosis.

BAY-8400

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  Catalog
Abmole Inhibitor Catalog




Keywords: ZL-2201 supplier, DNA-PK, inhibitors, activators

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