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XZ739, a Cereblon-dependent PROTAC BCL-XL (Bcl-2 family member) degrader with a DC50 value of 2.5 nM in MOLT-4 cells after 16 h treatment. XZ739 also induces cell death through caspase-mediated apoptosis.
| Molecular Weight | 1349.99 |
| Formula | C65H76ClF3N8O12S3 |
| CAS Number | 2365172-19-4 |
| Form | Solid |
| Solubility (25°C) | DMSO 20 mg/mL (ultrasonic) |
| Storage | -20°C, sealed |
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