Certificate of Analysis
| Product Name: | XZ739 |
| Catalog Number: | M29541 |
| CAS Number: | 2365172-19-4 |
Physical and Chemical Properties
| Formula: | C65H76ClF3N8O12S3 |
| Molecular Weight: | 1349.99 |
| Form: | Solid |
| Solubility: | DMSO 20 mg/mL (ultrasonic) |
| Storage: | -20°C, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | XZ739, a Cereblon-dependent PROTAC BCL-XL (Bcl-2 family member) degrader with a DC50 value of 2.5 nM in MOLT-4 cells after 16 h treatment. XZ739 also induces cell death through caspase-mediated apoptosis. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |