All AbMole products are for research use only, cannot be used for human consumption.
Xanthine 5' -monophosphate (XMP) is an intermediate of purine metabolism and a product of rate-limiting step in guanosine production, which plays an important role in the synthesis of DNA, RNA and glycoproteins. XMP is produced by inosin-5 '-monophosphate via IMP dehydrogenase (IMPDH). IMPDH inhibitors, including ribavirin and myophenolate, have potential applications as antiviral and anticancer compounds.
Cell Rep. 2024 Sep 24;43(9):114737.
In situ chemoproteomic profiling reveals itaconate inhibits de novo purine biosynthesis in pathogens
Xanthosine 5'-monophosphate sodium salt purchased from AbMole
| Molecular Weight | 408.17 |
| Formula | C10H11N4Na2O9P |
| CAS Number | 25899-70-1 |
| Form | Solid |
| Solubility (25°C) | Water ≥ 200 mg/mL |
| Storage | 4°C, dry, sealed |
| Related DNA/RNA Synthesis Products |
|---|
| Tetrahydrouridine
Tetrahydrouridine (THU) is potent inhibitor of cytidine deaminase (CDA), which competitively blocks the enzyme's active site more effectively than intrinsic cytidine. |
| Crisnatol
Crisnatol (BWA770U) is a member of the arylmethylaminopropanediol class of DNA intercalators. Crisnatol shows in vitro cytotoxicity against human breast cancer cells. Crisnatol (BWA770U) is also an orally active and anticancer agent. |
| Caf1-IN-1
Caf1-IN-1 is inhibitor for ribonuclease Caf1 with an IC50 of 0.59 µM. Caf1-IN-1 is also a weak inhibitor for poly(A)-specific ribonuclease (PARN) with IC50 of 23.9 µM. |
| BMH-22
BMH-22, a benzonaphthyridin, is a RNA polymerase I (Pol I) transcription inhibitor independent of p53 function. |
| Lomibuvir
Lomibuvir (VX-222), a selective, non-nucleoside polymerase inhibitor, targets thumb pocket 2 of the HCV NS5B polymerase (RdRp) with a Kd of 17 nM. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
