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Xanthine 5' -monophosphate (XMP) is an intermediate of purine metabolism and a product of rate-limiting step in guanosine production, which plays an important role in the synthesis of DNA, RNA and glycoproteins. XMP is produced by inosin-5 '-monophosphate via IMP dehydrogenase (IMPDH). IMPDH inhibitors, including ribavirin and myophenolate, have potential applications as antiviral and anticancer compounds.
Cell Rep. 2024 Sep 24;43(9):114737.
In situ chemoproteomic profiling reveals itaconate inhibits de novo purine biosynthesis in pathogens
Xanthosine 5'-monophosphate sodium salt purchased from AbMole
Molecular Weight | 408.17 |
Formula | C10H11N4Na2O9P |
CAS Number | 25899-70-1 |
Form | Solid |
Solubility (25°C) | Water ≥ 200 mg/mL |
Storage | 4°C, dry, sealed |
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