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WAY-652848

Cat. No. M20272

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WAY-652848 Structure
Synonym:

SPHINX

Size Price Availability Quantity
2mg USD 130  USD130 In stock
5mg USD 200  USD200 In stock
10mg USD 300  USD300 In stock
25mg USD 450  USD450 In stock
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Quality Control & Documentation
Biological Activity

WAY-652848 is a selective inhibitor of SRPK1 with an IC50 value of 0.58 μM.WAY-652848 effectively reduces choroidal neovascularization (CNV) in vivo, and can be used in the study of age-related macular degeneration.

Chemical Information
Molecular Weight 354.32
Formula C17H17F3N2O3
CAS Number 848057-98-7
Solubility (25°C) DMSO 10mM
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Related SRPK Products
MSC-1186

MSC-1186 is a highly selective pan-SRPK inhibitor with activity against SRPK1, SRPK2, and SRPK3 with IC50 values of 2.7 nM, 81 nM, and 0.6 nM, respectively.MSC-1186 can be used in cancer research.

SRPKIN-1 

SRPKIN-1 is a covalent and irreversible SRPK1/2 inhibitor with IC50s of 35.6 and 98 nM, respectively. Anti-angiogenesis effect.

SPHINX31

SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1) with IC50 of 5.9 nM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1).

SRPIN340

SRPIN340 is a selective SRPK inhibitor with Ki of 0.89 μM for SRPK1, showing no significant inhibitory activity against more than 140 other kinases.

  Catalog
Abmole Inhibitor Catalog




Keywords: WAY-652848, SPHINX supplier, SRPK, inhibitors, activators

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