SRPK Serine-arginine protein kinases

Cat.No.	Name	Information
M20272	WAY-652848	WAY-652848 is a selective inhibitor of SRPK1 with an IC50 value of 0.58 μM.WAY-652848 effectively reduces choroidal neovascularization (CNV) in vivo, and can be used in the study of age-related macular degeneration.
M10598	SPHINX31	SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1) with IC50 of 5.9 nM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1).
M3029	SRPIN340	SRPIN340 is a selective SRPK inhibitor with K_i of 0.89 μM for SRPK1, showing no significant inhibitory activity against more than 140 other kinases.
M49414	MSC-1186	MSC-1186 is a highly selective pan-SRPK inhibitor with activity against SRPK1, SRPK2, and SRPK3 with IC50 values of 2.7 nM, 81 nM, and 0.6 nM, respectively.MSC-1186 can be used in cancer research.
M29190	SRPKIN-1	SRPKIN-1 is a covalent and irreversible SRPK1/2 inhibitor with IC50s of 35.6 and 98 nM, respectively. Anti-angiogenesis effect.