Free shipping on all orders over $ 500

Vidofludimus

Cat. No. M4876

All AbMole products are for research use only, cannot be used for human consumption.

Vidofludimus Structure
Synonym:

SC12267, 4SC-101

Size Price Availability Quantity
10mM*1mL in DMSO USD 60  USD60 In stock
1mg USD 40  USD40 In stock
5mg USD 75  USD75 In stock
10mg USD 120  USD120 In stock
25mg USD 240  USD240 In stock
50mg USD 370  USD370 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Vidofludimus (4SC-101; SC12267) is an immunosuppressant that inhibits DHODH and inhibits il-17 secretion without affecting lymphocyte proliferation.

Chemical Information
Molecular Weight 355.36
Formula C20H18FNO4
CAS Number 717824-30-1
Solubility (25°C) DMSO 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Kulkarni OP, et.al. Am J Pathol. 4SC-101, a novel small molecule dihydroorotate dehydrogenase inhibitor, suppresses systemic lupus erythematosus in MRL-(Fas)lpr mice.

Related DHODH Products
DHODH-IN-13

DHODH-IN-13 is a hydroxyfurazan analog of A771726 and a dihydroorotic acid dehydrogenase (DHODH) inhibitor with an IC50 of 4.3 μM for hepatic DHODH in rats.DHODH-IN-13 can be used in rheumatoid arthritis-related studies.

DHODH-IN-12

DHODH-IN-12 is a Leflunomide derivative and a weak inhibitor of dihydroorotic acid dehydrogenase (DHODH), with a pKa of 5.07.

hDHODH-IN-5

hDHODH-IN-5 is a human dihydroorotic acid dehydrogenase (DHODH) inhibitor with an IC50 of 0.91 μM. hDHODH-IN-7 induces differentiation of acute myeloid leukemia cells.

DHODH-IN-8

DHODH-IN-8 is an inhibitor of human and Plasmodium falciparum dihydroorotic acid dehydrogenase (DHODH) with IC50s of 0.13 μM and 47.4 μM and Ki of 0.016 μM and 5.6 μM, respectively.DHODH-IN-8 exhibits antimalarial activity.

DHODH-IN-14

DHODH-IN-14 is a hydroxyfurazan analog of A771726 and a dihydroorotic acid dehydrogenase (DHODH) inhibitor with an IC50 of 0.49 μM for hepatic DHODH in rats.DHODH-IN-14 can be used in rheumatoid arthritis-related studies.

  Catalog
Abmole Inhibitor Catalog




Keywords: Vidofludimus, SC12267, 4SC-101 supplier, DHODH, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.