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Valinomycin

Cat. No. M8842

All AbMole products are for research use only, cannot be used for human consumption.

Valinomycin Structure
Synonym:

NSC 122023

Size Price Availability Quantity
1mg USD 30  USD30 In stock
5mg USD 50  USD50 In stock
10mg USD 70  USD70 In stock
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Quality Control & Documentation
Biological Activity

Valinomycin is a K+-selective ionophoric cyclodepsipeptide; potassium ionophore which uncouples oxidative phosphorylation, induces apoptosis in murine thymocytes, inhibits NGF-induced neuronal differentiation and antagonizes ET-induced vasoconstriction.

Chemical Information
Molecular Weight 1111.32
Formula C54H90N6O18
CAS Number 2001-95-8
Form Solid
Solubility (25°C) DMSO: ≥10 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Daniel J Watson, et al. Discovery of Novel Cyclic Ethers with Synergistic Antiplasmodial Activity in Combination with Valinomycin

[2] ZhangFei Su, et al. Ion-Pairing Mechanism for the Valinomycin-Mediated Transport of Potassium Ions across Phospholipid Bilayers

[3] Dong Zhang, et al. Valinomycin as a potential antiviral agent against coronaviruses: A review

[4] Jiř Czernek, et al. Polymorphic Forms of Valinomycin Investigated by NMR Crystallography

[5] Magdalena Anna Kroteń, et al. Cereulide and valinomycin, two important natural dodecadepsipeptides with ionophoretic activities

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Keywords: Valinomycin, NSC 122023 supplier, Antibiotic, inhibitors, activators

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