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Valanafusp alfa

Cat. No. M24820

All AbMole products are for research use only, cannot be used for human consumption.

Valanafusp alfa Structure
Synonym:

AGT-181; HIRMAb-IDUA

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Quality Control & Documentation
Biological Activity

Valanafusp alfa (AGT-181) is a brain penetrating recombinant fusion protein of a chimeric monoclonal antibody against the human insulin receptor (HIR) and human iduronidase (IDUA). Valanafusp alfa can be used for the research of Mucopolysaccharidosis type I (MPS I) .

Chemical Information
CAS Number 1815583-32-4
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Ruben J Boado, et al. Drug Metab Dispos. Glycemic control and chronic dosing of rhesus monkeys with a fusion protein of iduronidase and a monoclonal antibody against the human insulin receptor

[2] Ruben J Boado, et al. J Biotechnol. AGT-181: expression in CHO cells and pharmacokinetics, safety, and plasma iduronidase enzyme activity in Rhesus monkeys

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Keywords: Valanafusp alfa, AGT-181; HIRMAb-IDUA supplier, Insulin Receptor, inhibitors, activators

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