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KU14R has been shown to block the effects of the atypical I(3) agonist efaroxan at the level of the ATP-sensitive K(+) (K(ATP)) channel in isolated pancreatic islet beta cells, but its effects in vivo are not known. KU14R does not act as an antagonist of either efaroxan or S22068 at an imidazoline site in vivo.KU-14R, an I(3)-R antagonist, partially attenuated responses to IAA-RP.
| Molecular Weight | 214.26 |
| Formula | C13H14N2O |
| CAS Number | 189224-48-4 |
| Solubility (25°C) | DMSO 100 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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