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Uzansertib (INCB053914) is an orally active, ATP-competitive pan-PIM kinase inhibitor with IC50s of 0.24 nM, 30 nM, 0.12 nM for PIM1, PIM2, PIM3, respectively. Uzansertib has broad anti-proliferative activity against a variety of hematologic tumor cell lines.
| Molecular Weight | 513.51 |
| Formula | C26H26F3N5O3 |
| CAS Number | 1620012-39-6 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Related Pim Products |
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| 10-DEBC
10-DEBC is a selective Akt inhibitor. |
| R8-T198wt
R8-T198wt is a cell-permeable carboxyl-terminal p27Kip1 peptide exhibits anti-tumor activity by inhibiting Pim-1 kinase. |
| FD1024
FD1024 is PIM inhibitor (IC50s: 1.96, 38.9, 4.17 nM for PIM1, 2, 3). |
| Pim-1 kinase inhibitor 5
Pim-1 kinase inhibitor 5 is a Pim-1 kinase inhibitor (IC50: 0.61 μM). |
| Pim-1 kinase inhibitor 4
Pim-1 kinase inhibitor 4 is a Pim-1 kinase inhibitor (IC50: 17.01 nM). |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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