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Hispidulin is a natural flavonoid with a wide range of biological activities. Hispidulin is an inhibitor of PIM-1 with IC50 value of 2.71 μM. Hispidulin induces apoptosis through mitochondrial dysfunction and inhibition of P13k/Akt signalling pathway in HepG2 cancer cells. Hispidulin exerts anti-osteoporotic and bone resorption attenuating effects via activating the AMPK signaling pathway.
| Molecular Weight | 300.26 |
| Formula | C16H12O6 |
| CAS Number | 1447-88-7 |
| Form | Solid |
| Solubility (25°C) | DMSO ≥ 30 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Kacper Kut, et al. Antioxidant properties of hispidulin
[3] Kaili Liu, et al. Hispidulin: A promising flavonoid with diverse anti-cancer properties
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