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Triheptanoin

Cat. No. M10068
Triheptanoin Structure
Synonym:

IND106011; UX007

Size Price Availability Quantity
5mg USD 420 In stock
10mg USD 820 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

Triheptanoin is a fatty acid metabolic modulator. Triheptanoin is potentially used for the treatment of fatty acid oxidation disorders and GLUT1.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 428.61
Formula C24H44O6
CAS Number 620-67-7
Purity >98%
Solubility DMSO
Storage at -20°C
References

Triheptanoin Mitigates Brain ATP Depletion and Mitochondrial Dysfunction in a Mouse Model of Alzheimer's Disease
Xiaodong Yuan, et al. J Alzheimers Dis. 2020;78(1):425-437. PMID: 33016909.

Therapeutic potential of triheptanoin in metabolic and neurodegenerative diseases
Zeinab Wehbe, et al. J Inherit Metab Dis. 2020 May;43(3):385-391. PMID: 31778232.

Triheptanoin protects against status epilepticus-induced hippocampal mitochondrial dysfunctions, oxidative stress and neuronal degeneration
Kah Ni Tan, et al. J Neurochem. 2018 Feb;144(4):431-442. PMID: 29222946.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Triheptanoin, IND106011; UX007 supplier, FAS, inhibitors

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