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Trifarotene (CD5789) is a potent and selective RARγ agonist. Trifarotene (CD5789) shows ∼65-fold and ∼16-fold selectivitiy for the RARγ (EC50=7.7 nM) over RARα (EC50=500 nM) and RARβ (EC50=125 nM), respectively.
| Molecular Weight | 459.58 |
| Formula | C29H33NO4 |
| CAS Number | 895542-09-3 |
| Form | Solid |
| Solubility (25°C) | DMSO 200 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Piyu Parth Naik. Dermatol Res Pract. Trifarotene: A Novel Therapeutic Option for Acne
[2] No authors listed. Trifarotene
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