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Tricetin

Cat. No. M30231

All AbMole products are for research use only, cannot be used for human consumption.

Tricetin Structure

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Quality Control & Documentation
Biological Activity

Tricetin is a potent competitive inhibitor of the Keap1-Nrf2 Protein Protein Interaction (PPI). Tricetin protects against 6-OHDA-induced neurotoxicity in Parkinson's disease model by activating Nrf2/HO-1 signaling pathway and preventing mitochondria-dependent apoptosis pathway.

Chemical Information
Molecular Weight 302.24
Formula C15H10O7
CAS Number 520-31-0
Form Solid
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Hsin-Yu Ho, et al. Am J Chin Med. Tricetin Suppresses Migration and Presenilin-1 Expression of Nasopharyngeal Carcinoma through Akt/GSK-3β Pathway

[2] Luming Cai, et al. Int Immunopharmacol. Natural flavone tricetin suppresses oxidized LDL-induced endothelial inflammation mediated by Egr-1

[3] Fang-Fang Sun, et al. Oxid Med Cell Longev. Tricetin Protects Rat Chondrocytes against IL-1 β-Induced Inflammation and Apoptosis

[4] Ming-Hsien Chien, et al. Int J Mol Sci. Tricetin Induces Apoptosis of Human Leukemic HL-60 Cells through a Reactive Oxygen Species-Mediated c-Jun N-Terminal Kinase Activation Pathway

[5] Pin-Yu Chang, et al. Environ Toxicol. Tricetin inhibits human osteosarcoma cells metastasis by transcriptionally repressing MMP-9 via p38 and Akt pathways

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Keywords: Tricetin supplier, Apoptosis, inhibitors, activators

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