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Tribromoethanol for ready use

Cat. No. M5358
Tribromoethanol for ready use Structure
Synonym:

Tribromoethyl alcohol

Size Price Availability Quantity
10mL USD 50  USD50 In stock
100mL USD 250  USD250 In stock
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Quality Control & Documentation
Biological Activity

2,2,2-Tribromoethanol is an injectable anesthetic agent used in mice.

Chemical Information
Molecular Weight 282.76
Formula C2H3Br3O
CAS Number 75-80-9
Form Solution
Storage 2-8°C, protect from light
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Maheras KJ, et al. J Neurosci Methods. Increased anesthesia time using 2,2,2-tribromoethanol-chloral hydrate with low impact on mouse psychoacoustics.

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