All AbMole products are for research use only, cannot be used for human consumption.
Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent, works by inhibiting the synthesis of viral RNA and DNA and replication of genomic fragments. Triazavirin is shown active in inhibition of the tick-borne encephalitis virus reproduction (strain Sofiin) by accumulation in the SKEV cell culture.
In high doses (200-400 mg/kg) Triazavirin moderately protects the infected animals. A significant increase of the animal lifespan in the test groups (from 4.1 to 4.8 days) and a statistically valid decrease of the virus accumulation in the target organ are observed.
Antibiot Khimioter. 2015;60(7-8):11-3.
Investigation of Therapeutic Efficacy of Triazavirin Against Experimental Forest-Spring Encephalitis on Albino Mice
Triazavirin purchased from AbMole
Antibiot Khimioter. 2014;59(1-2):3-5.
Investigation of Triazavirin antiviral activity against tick-borne encephalitis pathogen in cell culture
Triazavirin purchased from AbMole
| Molecular Weight | 286.20 |
| Formula | C5H7N6NaO5S |
| CAS Number | 928659-17-0 |
| Solubility (25°C) | DMSO ≥ 60 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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