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Tigecycline tetramesylate

Cat. No. M13477

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Tigecycline tetramesylate Structure
Synonym:

GAR-936 tetramesylate

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10mg USD 60 4-7 Days
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Quality Control & Documentation
Biological Activity

Tigecycline tetramesylate (GAR-936 tetramesylate) is a broad-spectrum glycylcycline antibiotic. The mean inhibitory concentration (MIC) of Tigecycline for E. coli (MG1655 strain) is approximately 125 ng/mL. MIC50 and MIC90 are 1 and 2 mg/L for Acinetobacter baumannii (A. baumannii), respectively.

Chemical Information
Molecular Weight 970.07
Solubility (25°C) DMSO 90 mg/mL
Water 50 mg/mL
Storage 2-8°C, dry, sealed
References

[1] Stamatis Karakonstantis, et al. Infection. Treatment options for K. pneumoniae, P. aeruginosa and A. baumannii co-resistant to carbapenems, aminoglycosides, polymyxins and tigecycline: an approach based on the mechanisms of resistance to carbapenems

[2] Nannan Cui, et al. Int J Clin Pharm. Tigecycline-induced coagulopathy: a literature review

[3] Jian Sun, et al. Nat Microbiol. Plasmid-encoded tet(X) genes that confer high-level tigecycline resistance in Escherichia coli

[4] Tao He, et al. Nat Microbiol. Emergence of plasmid-mediated high-level tigecycline resistance genes in animals and humans

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