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Tetracycline hydrochloride

Cat. No. M3207

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Tetracycline hydrochloride Structure
Synonym:

NCI-c55561; Tetracycline HCl

Size Price Availability Quantity
Free Sample (0.5-1 mg)  USD 0 In stock
500mg USD 40  USD40 In stock
1g USD 55  USD55 In stock
5g USD 90  USD90 In stock
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Quality Control & Documentation
Biological Activity

Tetracycline hydrochloride is a hydrochloride salt of tetracycline that is a broad-spectrum polyketide antibiotic. Tetracycline binds to the 30S subunit of microbial ribosomes. Tetracycline inhibits protein synthesis by blocking the attachment of charged aminoacyl-tRNA. Thus tetracycline prevents introduction of new amino acids to the nascent peptide chain. The action is usually inhibitory and reversible upon withdrawal of the drug. Resistance to the tetracycline results from changes in permeability of the microbial cell envelope. In susceptible cells, the tetracycline is concentrated from the environment and does not readily leave the cell. Tetracycline hydrochloride is used in the treatment of bacterial infections, such as urinary tract infections, acne, gonorrhea, chlamydia, and others.

Chemical Information
Molecular Weight 480.9
Formula C22H24N2O8.HCl
CAS Number 64-75-5
Solubility (25°C) Water 50 mg/mL
DMSO 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] W Y Gong, et al. Beijing Da Xue Xue Bao Yi Xue Ban. Nano-sized bioactive glass enhances osteogenesis of critical bone defect in rabbits

[2] Chatzispyrou IA, et al. Cancer Res. Tetracycline antibiotics impair mitochondrial function and its experimental use confounds research.

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Keywords: Tetracycline hydrochloride, NCI-c55561; Tetracycline HCl supplier, Antibiotic, inhibitors, activators

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