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TAK-659 is a highly potent, selective, reversible and orally available dual inhibitor of spleen tyrosine kinase (SYK) and fms related tyrosine kinase 3 (FLT3), with an IC50 of 3.2 nM and 4.6 nM for SYK and FLT3, respectively. TAK-659 induces cell death in tumor cells but not in nontumor cells, and with potential for the treatment of chronic lymphocytic leukemia (CLL).
| Molecular Weight | 344.39 |
| Formula | C17H21FN6O |
| CAS Number | 1312691-33-0 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Related Syk Products |
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