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GSK143 

Cat. No. M57218

All AbMole products are for research use only, cannot be used for human consumption.

GSK143  Structure

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Quality Control & Documentation
Biological Activity

GSK143 is an orally active and highly selective spleen tyrosine kinase (SYK) inhibitor with a pIC50 of 7.5.

Chemical Information
Molecular Weight 342.4
Formula C17H22N6O2
CAS Number 1240390-27-5
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Related Syk Products
PRT062607

PRT062607(P505-15; PRT-2607; BIIB-057) is a highly specific and potent inhibitor of Syk with IC50 of 1-2 nM; >80-fold selective for Syk than Fgr, Lyn, FAK, Pyk2 and Zap70.

GSK143 dihydrochloride 

GSK143 dihydrochloride is an orally active and highly selective spleen tyrosine kinase (SYK) inhibitor with a pIC50 of 7.5.

Syk Kinase Peptide Substrate

Syk Kinase Peptide Substrate is a Syk kinase peptide substrate.

TOP1288

TOP1288 is an SRC/Syk/p38α inhibitor for studies related to ulcerative colitis.

R343

R343 is an immunoglobulin E (IgE) as well as spleen tyrosine kinase (Syk) inhibitor for studies related to allergic asthma and non-small cell lung cancer.

  Catalog
Abmole Inhibitor Catalog




Keywords: GSK143  supplier, Syk, inhibitors, activators

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