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TAK-041 is a first-in-class, selective GPR139 agonist with an EC50 of 22 nM. TAK-041 can be used to study negative symptoms of schizophrenia.
| Molecular Weight | 392.33 |
| Formula | C18H15F3N4O3 |
| CAS Number | 1929519-13-0 |
| Form | Solid |
| Solubility (25°C) | DMSO ≥ 60 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related GPR/FFAR Products |
|---|
| GPR84 antagonist 8
GPR84 antagonist 8 is a selective GPR84 antagonist. |
| ML191
ML-191 is an antagonist of GPR55. |
| CID1172084
CID1172084 is a selective GPR55 agonist (EC50=0.16 μM). |
| ML 145
ML 145 is a selective and competitive human GPR35/CXCR8 antagonist with an IC50/EC50 of 20.1 nM. |
| PSN 375963 hydrochloride
PSN 375963 hydrochloride is a potent GPR119 agonist, with EC50s of 8.4 and 7.9 μM for human and mouse GPR119, respectively. |
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