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T-448 is a specific, orally active and irreversible inhibitor of lysine-specific demethylase 1 (LSD1, an H3K4 demethylase), with an IC50 of 22 nM. T-448 enhances H3K4 methylation in primary cultured rat neurons.
| Molecular Weight | 386.5 |
| Formula | C17H20N4OS.1/2C4H4O4 |
| CAS Number | 1597426-53-3 |
| Form | Solid |
| Solubility (25°C) | DMSO 16.67 mg/mL (ultrasonic) |
| Storage | -20°C, sealed |
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