Certificate of Analysis
| Product Name: | T-448 |
| Catalog Number: | M28649 |
| CAS Number: | 1597426-53-3 |
Physical and Chemical Properties
| Formula: | C17H20N4OS.1/2C4H4O4 |
| Molecular Weight: | 386.5 |
| Form: | Solid |
| Solubility: | DMSO 16.67 mg/mL (ultrasonic) |
| Storage: | -20°C, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | T-448 is a specific, orally active and irreversible inhibitor of lysine-specific demethylase 1 (LSD1, an H3K4 demethylase), with an IC50 of 22 nM. T-448 enhances H3K4 methylation in primary cultured rat neurons. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |