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Synucleozid

Cat. No. M30195

All AbMole products are for research use only, cannot be used for human consumption.

Synucleozid Structure
Synonym:

NSC 377363

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Quality Control & Documentation
Biological Activity

Synucleozid (NSC 377363) is a potent inhibitor of the SNCA mRNA that encodes α-synuclein protein. Synucleozid selectively targets the α-synuclein mRNA 5′ UTR at the designed IRE site, decreases the amount of SNCA mRNA loaded into polysomes and thereby inhibits SNCA translation. Synucleozid has the potential for the investigation of Parkinson’s disease.

Chemical Information
Molecular Weight 368.43
Formula C22H20N6
CAS Number 502139-01-7
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Peiyuan Zhang, et al. Proc Natl Acad Sci U S A. Translation of the intrinsically disordered protein α-synuclein is inhibited by a small molecule targeting its structured mRNA

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  Catalog
Abmole Inhibitor Catalog




Keywords: Synucleozid, NSC 377363 supplier, DNA/RNA Synthesis, inhibitors, activators

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