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Sulfanilamide is a sulfonamide antibacterial. It is a sulfonamide antibacterial. Chemically, it is a molecule containing the sulfonamide functional group attached to an aniline. As an antibiotic, it functions by competitively inhibiting (ie, by acting as a substrate analogue) enzymatic reactions involving para-aminobenzoic acid (PABA). PABA is needed in enzymatic reactions that produce folic acid which acts as a coenzyme in the synthesis of purine, pyrimidine and other amino acids.
| Cell Experiment | |
|---|---|
| Cell lines | |
| Preparation method | |
| Concentrations | |
| Incubation time | |
| Animal Experiment | |
|---|---|
| Animal models | Male Sprague-Dawley rats |
| Formulation | Thoroughly mixed into the daily ration of pulverized food and compounded into pellets. |
| Dosages | 100 mg/kg |
| Administration | Orally taken every day |
| Molecular Weight | 172.2 |
| Formula | C6H8N2O2S |
| CAS Number | 63-74-1 |
| Form | Solid |
| Solubility (25°C) | DMSO 30 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] R N CHAUDHURI. Sulphonamides
[2] R N CHAUDHURI. Sulphonamides
[4] S T MADSEN. PROTEIN-BINDING OF SULFONAMIDES
[5] No authors listed. J Am Med Assoc. SULFAMETHOXYPYRIDAZINE
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