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Etidronic acid disodium

Cat. No. M20873
Etidronic acid disodium Structure
Synonym:

Etidronate disodium; HEDPA disodium; HEDP disodium

Size Price Availability Quantity
500mg USD 38.4  USD48 In stock
1g USD 60  USD75 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Sodium Etidronate (Didronel, EHDP, Etidronic acid) is a non-aminobisphosphonate that exhibits protein tyrosine phosphatase (PTP) inhibitory activity.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 249.99
Formula C2H6Na2O7P2
CAS Number 7414-83-7
Purity >99%
Solubility Water 50 mg/mL
Storage at -20°C
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Keywords: Etidronic acid disodium, Etidronate disodium; HEDPA disodium; HEDP disodium supplier, Phosphatase, inhibitors

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