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SKA-111

Cat. No. M42237

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SKA-111 Structure

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Quality Control & Documentation
Biological Activity

SKA-111 is a selective activator of potassium phannel KCa 3.1 , evokes KCa 3.1 membrane hyperpolarization in porcine endothelial cell.

Chemical Information
Molecular Weight 214.29
Formula C12H10N2S
CAS Number 1369170-24-0
Form Solid
Solubility (25°C) DMSO 100 mg/mL (Need ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Heesung Shim et al. Front Pharmacol. The Trials and Tribulations of Structure Assisted Design of KCa Channel Activators

[2] Aida Oliván-Viguera et al. Basic Clin Pharmacol Toxicol. Vascular Reactivity Profile of Novel KCa 3.1-Selective Positive-Gating Modulators in the Coronary Vascular Bed

[3] Nichole Coleman et al. Mol Pharmacol. New positive Ca2+-activated K+ channel gating modulators with selectivity for KCa3.1

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  Catalog
Abmole Inhibitor Catalog




Keywords: SKA-111 supplier, Potassium Channel, inhibitors, activators

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