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Semilicoisoflavone B, an isoflavone, mainly derived from Glycyrrhiza uralensis Fisch.. Semilicoisoflavone B reduces amyloid β (Aβ) secretion by inhibiting β-secretase-1 (BACE1) expression and activity. Semilicoisoflavone B decreases BACE1 expression mainly through increasing PPARγ expression and inhibiting STAT3 phosphorylation.
| Molecular Weight | 352.34 |
| Formula | C20H16O6 |
| CAS Number | 129280-33-7 |
| Form | Solid |
| Solubility (25°C) | DMSO 50 mg/mL (ultrasonic and warming and heat to 60°C) |
| Storage | -20°C, protect from light, dry, sealed |
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