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Ropivacaine hydrochloride is a potent sodium channel blocker and blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese. Ropivacaine is also an inhibitor of K2P (two-pore domain potassium channel) TREK-1 with an IC50 of 402.7 μM in COS-7 cell's membrane. Ropivacaine is widely used for neuropathic pain management in vivo.
| Molecular Weight | 310.86 |
| Formula | C17H27ClN2O |
| CAS Number | 98717-15-8 |
| Solubility (25°C) | DMSO 10 mg/mL Water 10 mg/mL |
| Storage | 2-8°C, dry, sealed |
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