Free shipping on all orders over $ 500

Rocatinlimab

Cat. No. M25161

All AbMole products are for research use only, cannot be used for human consumption.

Rocatinlimab Structure
Synonym:

AMG 451; KHK4083

Size Price Availability
1mg USD 330 3-4 Weeks
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Rocatinlimab (AMG 451) (KHK4083) is a fully human, non-fucosylated, immunoglobulin G1 (IgG1) anti-OX40 monoclonal antibody. Rocatinlimab can be used for the research of atopic dermatitis (AD).

Chemical Information
CAS Number 2431972-52-8
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Ana Maria Lé, et al. Pharmaceutics. OX40-OX40L Inhibition for the Treatment of Atopic Dermatitis-Focus on Rocatinlimab and Amlitelimab

[2] Emma Guttman-Yassky, et al. Lancet. An anti-OX40 antibody to treat moderate-to-severe atopic dermatitis: a multicentre, double-blind, placebo-controlled phase 2b study

Related TNF Receptor Products
Atrosab

Atrosab is a humanized IgG1 antagonistic anti-TNFR1 antibody. Atrosab inhibits TNF-mediated Apoptosis induction and IL-6 and IL-8 production. Atrosab reduces neurological deficits.

Mesaconitine

Mesaconitine is the main active ingredient of Aconitum and has many pharmaceutical effects.

Hypaconitine

Hypaconitine is a highly toxic natural active ingredient isolated from aconitum species, which is widely used to study rheumatism.

Shikonin

Shikonin (C.I. 75535, Anchusin, Anchusa acid, Alkanna Red, Isoarnebin 4, NSC 252844) is an effective and specific inhibitor of Pyruvate kinase M2 (PKM2). Shikonin is the main ingredient of Lithosia, a Chinese herb with a variety of biological activities. Shikonin acts as an anti-inflammatory by inhibiting tumor necrosis factor-α (TNF-α), Proteasome can inhibit the activation of nuclear factor-κB (NF-κB) signaling pathway.

Forsythoside B

Forsythoside B inhibits TNF-alpha, IL-6, IκB and modulate NF-κB.

  Catalog
Abmole Inhibitor Catalog




Keywords: Rocatinlimab, AMG 451; KHK4083 supplier, TNF Receptor, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.