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Retinoic acid is A metabolite of vitamin A and plays an important role in cell growth, differentiation and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors with an IC50 of 14 nM for RARα/β/γ. The Kd value of Retinoic acid combined with PPARβ/δ is 17 nM. Retinoic acid inhibits the transcription factor Nrf2 by activating Retinoic acid receptors.
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Retinoic acid purchased from AbMole
| Molecular Weight | 300.44 |
| Formula | C20H28O2 |
| CAS Number | 302-79-4 |
| Solubility (25°C) | DMSO 45 mg/mL (ultrasonic and warming) |
| Storage | -20°C, protect from light, dry, sealed |
[1] Samarawickrama C, et al. Surv Ophthalmol. Retinoic acid and the ocular surface.
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