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(Rac)-Calpain Inhibitor XII is a reversible and selective inhibitor of calpain I (μ-calpain, Ki=19 nM). (Rac)-Calpain Inhibitor XII has lower affinities for calpain II (m-calpain, Ki=120 nM) and cathepsin B (Ki=750 nM). (Rac)-Calpain Inhibitor XII has the potential for studying the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling, and cardiac response to injury.
| Molecular Weight | 482.57 |
| Formula | C26H34N4O5 |
| CAS Number | 181769-57-3 |
| Form | Solid |
| Solubility (25°C) | DMSO 15 mg/mL (Need ultrasonic and warming) |
| Storage | -20°C, sealed |
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