Certificate of Analysis
| Product Name: | (Rac)-Calpain Inhibitor XII |
| Catalog Number: | M28912 |
| CAS Number: | 181769-57-3 |
Physical and Chemical Properties
| Formula: | C26H34N4O5 |
| Molecular Weight: | 482.57 |
| Form: | Solid |
| Solubility: | DMSO 15 mg/mL (Need ultrasonic and warming) |
| Storage: | -20°C, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | (Rac)-Calpain Inhibitor XII is a reversible and selective inhibitor of calpain I (μ-calpain, Ki=19 nM). (Rac)-Calpain Inhibitor XII has lower affinities for calpain II (m-calpain, Ki=120 nM) and cathepsin B (Ki=750 nM). |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |