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(Rac)-BIO8898

Cat. No. M25497

All AbMole products are for research use only, cannot be used for human consumption.

(Rac)-BIO8898 Structure

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Quality Control & Documentation
Biological Activity

(Rac)-BIO8898 is a CD40-CD154 co-stimulatory interaction inhibitor. (Rac)-BIO8898 inhibits CD154 binding to CD40-Ig with an IC50 of 25 μM. BIO8898 acts by disrupting the structure of the constitutively trimeric CD40L molecule.

Chemical Information
Molecular Weight 909.13
Formula C53H64N8O6
CAS Number 402564-79-8
Solubility (25°C) DMSO
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Laura F Silvian, et al. ACS Chem Biol. Small molecule inhibition of the TNF family cytokine CD40 ligand through a subunit fracture mechanism

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  Catalog
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Keywords: (Rac)-BIO8898 supplier, TNF Receptor, inhibitors, activators

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