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Quercetin 3-gentiobioside

Cat. No. M18249
Quercetin 3-gentiobioside Structure
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Biological Activity

Quercetin 3-gentiobioside

Chemical Information
Molecular Weight 626.52
Formula C27H30O17
CAS Number 7431-83-6
Form Solid
Solubility (25°C) DMSO 90 mg/mL
Storage 4°C, protect from light, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Jing Yang, et al. Metabolites. Identification and Quantification of Flavonoids in Okra ( Abelmoschus esculentus L. Moench) and Antiproliferative Activity In Vitro of Four Main Components Identified

[2] Mina Kim, et al. Molecules. Response Surface Methodology for Optimization of Process Parameters and Antioxidant Properties of Mulberry ( Morus alba L.) Leaves by Extrusion

[3] Yoon Kyoung Lee, et al. Biomed Res Int. Inhibitory Effect of Chemical Constituents Isolated from Artemisia iwayomogi on Polyol Pathway and Simultaneous Quantification of Major Bioactive Compounds

[4] H Moriyama, et al. Yakugaku Zasshi. A stabilized flavonoid glycoside in heat-treated Cassia alata leaves and its structural elucidation

[5] H H Barakat, et al. Phytochemistry. Flavonoids of Ochradenus baccatus

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