All AbMole products are for research use only, cannot be used for human consumption.
Pyridostatin (RR82) is a G-quadruplex DNA stabilizing agent (Kd=490 nM). Pyridostatin promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Pyridostatin targets the proto-oncogene Src. Pyridostatin reduced SRC protein levels and SRC-dependent cellular motility in human breast cancer cells.
Molecular Weight | 596.64 |
Formula | C31H32N8O5 |
CAS Number | 1085412-37-8 |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[5] Michele Olivieri, et al. Cell. A Genetic Map of the Response to DNA Damage in Human Cells
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Caf1-IN-1 is inhibitor for ribonuclease Caf1 with an IC50 of 0.59 µM. Caf1-IN-1 is also a weak inhibitor for poly(A)-specific ribonuclease (PARN) with IC50 of 23.9 µM. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
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