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PKH-67 (green)

Cat. No. M21704
PKH-67 (green) Structure
Synonym:

PKH67

Size Price Availability Quantity
1mM*100uL in EtOH USD 300  USD300 In stock
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Quality Control & Documentation
Biological Activity

Chemical Information
Solubility (25°C) Ethanol
Storage 2-8°C, protect from light, sealed, stable for 6-12 months
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Lu Chen, et al. Theranostics. Exosomes derived from GDNF-modified human adipose mesenchymal stem cells ameliorate peritubular capillary loss in tubulointerstitial fibrosis by activating the SIRT1/eNOS signaling pathway

[2] Smart Ikechukwu Mbagwu, et al. Pathogens. Human Microglia Respond to Malaria-Induced Extracellular Vesicles

[3] Lihua Dong, et al. Int J Mol Sci. Xeno-Free Propagation of Spermatogonial Stem Cells from Infant Boys

[4] Kristine Buch Uldahl, et al. Sci Rep. Recognition of extremophilic archaeal viruses by eukaryotic cells: a promising nanoplatform from the third domain of life

[5] Vitor Y R Soares, et al. Neuro Oncol. Extracellular vesicles derived from human vestibular schwannomas associated with poor hearing damage cochlear cells

[6] M L Rand, et al. Cytometry. Concurrent measurement of the survival of two populations of rabbit platelets labeled with either two PKH lipophilic dyes or two concentrations of biotin

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