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Picrasidine I

Cat. No. M38835

All AbMole products are for research use only, cannot be used for human consumption.

Picrasidine I Structure

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Quality Control & Documentation
Biological Activity

Picrasidine I induces cell cycle arrest, and triggers cell apoptosis by downregulats ERK and Akt pathways. Picrasidine I inhibits the activation of MAPKs, NF-κB and ROS generation, and suppresses the expression of c-Fos and NFATc1.

Chemical Information
Molecular Weight 240.26
Formula C14H12N2O2
CAS Number 100234-59-1
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Hsin-Yu Ho et al. Int J Mol Sci. Picrasidine I Triggers Heme Oxygenase-1-Induced Apoptosis in Nasopharyngeal Carcinoma Cells via ERK and Akt Signaling Pathways

[2] Yuan-Ting Yang et al. Environ Toxicol. Anticancer effects of picrasidine I on oral squamous cell carcinoma

[3] Lingbo Kong et al. Cell Physiol Biochem. Picrasidine I from Picrasma Quassioides Suppresses Osteoclastogenesis via Inhibition of RANKL Induced Signaling Pathways and Attenuation of ROS Production

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Keywords: Picrasidine I supplier, Apoptosis, inhibitors, activators

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