Free shipping on all orders over $ 500

PF-06455943 

Cat. No. M28571

All AbMole products are for research use only, cannot be used for human consumption.

PF-06455943  Structure

Price and Availability

For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

PF-06455943 is a leucine rich repeat kinase 2 (LRRK2) inhibitor with IC50 value of 3 nM. PF-06455943 also is a PET radioligand. PF-06455943 can be used for the research of ADME/neuro PK characterization and Parkinson disease (PD).

Chemical Information
Molecular Weight 323.32
Formula C17H14FN5O
CAS Number 1527474-15-2
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Chi-Hyeon Yoo, et al. ACS Chem Neurosci. Evaluation of [18F]PF-06455943 as a Potential LRRK2 PET Imaging Agent in the Brain of Nonhuman Primates

[2] Zhen Chen, et al. J Med Chem. Imaging Leucine-Rich Repeat Kinase 2 In Vivo with 18F-Labeled Positron Emission Tomography Ligand

Related LRRK2 Products
CZC-54252 hydrochloride

CZC-54252 hydrochloride is a potent and selective LRRK2 inhibitor with IC50s of 1.28 nM and 1.85 nM for wild-type and G2019S LRRK2, respectively.

PF-06371900 

PF-06371900 is a potent and highly selective leucine rich repeat kinase 2 (LRRK2) inhibitor.

CZC-25146 hydrochloride

CZC-25146 is a potent selective and metabolically stable inhibitor of leucine-rich repeat kinase-2 (LRRK2) also known as dardarin or PARK8, a kinase with mutations linked to Parkinson’s disease.

  Catalog
Abmole Inhibitor Catalog




Keywords: PF-06455943  supplier, LRRK2, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.