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Pf-06409577 is a potent and selective allosteric activator of AMPK α1β1γ1 subtype with an EC50 value of 7 nM.
FEBS Open Bio. 2022 Oct;12(10):1761-1770.
PF‐06409577 inhibits renal cyst progression by concurrently inhibiting the mTOR pathway and CFTR channel activity
PF-06409577 purchased from AbMole
| Molecular Weight | 341.79 |
| Formula | C19H16ClNO3 |
| CAS Number | 1467057-23-3 |
| Solubility (25°C) | DMSO ≥ 30 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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