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PF-04957325 is a highly potent and selective PDE8 inhibitor, with IC50s of 0.7 nM and 0.3 nM for PDE8A and PDE8B, respectively.
| Molecular Weight | 400.38 |
| CAS Number | 1305115-80-3 |
| Solubility (25°C) | DMSO ≥ 90 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Mark J Turner, et al. Phosphodiesterase 8A Regulates CFTR Activity in Airway Epithelial Cells
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