All AbMole products are for research use only, cannot be used for human consumption.
Peretinoin is an oral acyclic retinoid with a vitamin A-like structure that targets retinoid nuclear receptors such as retinoid X receptor (RXR) and retinoic acid receptor (RAR). Peretinoin inhibits HCV RNA amplification and virus release by altering lipid metabolism with EC50 of 9 μM. Peretinoin (10-40 μM; 12-72 hours) exhibits suppressed the mRNA level of sphingosine kinase 1 (SPHK1) expression after 24 h treatment, even at 10 μM and more prominent after 72 h peretinoin treatment. Peretinoin (5 μM; 24 hours) up-regulates the expression of LC3B-II and increases autophagy flux in mouse primary hepatocytes.
| Molecular Weight | 302.45 |
| Formula | C20H30O2 |
| CAS Number | 81485-25-8 |
| Solubility (25°C) | DMSO 45 mg/mL |
| Storage | -20°C, protect from light, sealed |
| Related RAR/RXR Products |
|---|
| YCT529
YCT529 is a potent, selective and orally active RAR-α inhibitor. |
| LG101506
LG101506 is a selective and orally active RXR modulator with a Ki of 2.7 nM for RXRα. |
| ER 50891
ER-50891 is a potent antagonist of retinoic acid receptor α(RARα). |
| LG100754
LG100754 (UVI 2112) is a RXR dimers modulater. |
| AGN 196996
AGN 196996 is a potent and selective RARα antagonist with Ki value of 2 nM; little binding affinity for RARβ(Ki=1087 nM) and RARγ(Ki=8523 nM). |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
