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Peplomycin

Cat. No. M40865

All AbMole products are for research use only, cannot be used for human consumption.

Peplomycin Structure

Price and Availability

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Quality Control & Documentation
Biological Activity

Peplomycin is a peptide polyene compound derived from Streptomyces and a Bleomycin analog with high antitumor activity. In addition, Peplomycin induces a variety of skin abnormalities and induces apoptosis in oral squamous carcinoma SSCKN cells and lung fibrosis.

Chemical Information
Molecular Weight 1473.59
Formula C61H88N18O21S2
CAS Number 68247-85-8
Storage -20°C
References

[1] Y Asano et al. Br J Dermatol. A case of peplomycin-induced scleroderma

[2] Hidenori Umeki et al. Gan To Kagaku Ryoho. [Neoadjuvant intraarterial chemotherapy with nedaplatin, peplomycin and mitomycin C for advanced cervical cancer]

[3] S K Carter et al. Cancer Treat Rev. Peplomycin

[4] B Saulier et al. Carcinogenesis. Peplomycin. DNA breakage and in vivo inhibition of DNA polymerases and ligase from human normal and leukemic cells

[5] S Ikeda et al. Drugs Exp Clin Res. Peplomycin therapy for skin cancer in Japan

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Keywords: Peplomycin supplier, Apoptosis, inhibitors, activators

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