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Pam3CSK4 induces production of TNF-α and IL-6 in macrophages. Pam3CSK4 stimulates phosphorylation of p100/p110 and p60 in granulocytic-differentiated HL-60 cells. Pam3CSK4 promotes differentiation of naive CD4+ T cells into Th17 cells.
| Molecular Weight | 1510.24 |
| Formula | C81H156N10O13S |
| CAS Number | 112208-00-1 |
| Solubility (25°C) | 1 mg/ml in 50% Ethanol / water |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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