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Ozenoxacin

Cat. No. M19926
Ozenoxacin Structure
Size Price Availability Quantity
5mg USD 95  USD95 In stock
10mg USD 140  USD140 In stock
25mg USD 270  USD270 In stock
50mg USD 460  USD460 In stock
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Quality Control & Documentation
Biological Activity

Ozenoxacin is a quinolone antibiotic used for the treatment of impetigo.

Chemical Information
Molecular Weight 363.41
Formula C21H21N3O3
CAS Number 245765-41-7
Solubility (25°C) DMSO 5 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Sarah Eudaley. Am Fam Physician. Ozenoxacin (Xepi) for the Treatment of Impetigo

[2] Jordi Vila, et al. Expert Rev Anti Infect Ther. Ozenoxacin: a review of preclinical and clinical efficacy

[3] No authors listed. Ozenoxacin

[4] Christopher Wren, et al. Ann Pharmacother. Ozenoxacin: A Novel Topical Quinolone for Impetigo

[5] Jagdish K Sahu, et al. Curr Drug Discov Technol. Ozenoxacin: A Novel Drug Discovery for the Treatment of Impetigo

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