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NSC 185058 is an inhibitor of ATG4B, a major cysteine protease. NSC185058 inhibits ATG4B, the lipidation of LC3B, and autophagy without affecting the MTOR or PtdIns3K pathways.
| Molecular Weight | 215.27 |
| Formula | C11H9N3S |
| CAS Number | 39122-38-8 |
| Solubility (25°C) | DMSO ≥ 60 mg/mL |
| Storage | 4°C, protect from light |
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