Certificate of Analysis
| Product Name: | NSC 185058 |
| Catalog Number: | M20673 |
| CAS Number: | 39122-38-8 |
Physical and Chemical Properties
| Formula: | C11H9N3S |
| Molecular Weight: | 215.27 |
| Solubility: | DMSO ≥ 60 mg/mL |
| Storage: | 4°C, protect from light |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | NSC 185058 is an inhibitor of ATG4B, a major cysteine protease. NSC185058 inhibits ATG4B, the lipidation of LC3B, and autophagy without affecting the MTOR or PtdIns3K pathways. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |