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Nogalamycin is an anthracyclinone antibiotic. Nogalamycin is a potent antibiotic against Gram-positive bacteria, also has cytotoxicity against certain tumor cells. Nogalamycin is produced by Streptomyces nogalater var. Nogalater. Nogalamycin selectively inhibits RNA synthesis after binding to DNA template. Nogalamycin can be used for researching anticancer.
| Molecular Weight | 787.8 |
| Formula | C39H49NO16 |
| CAS Number | 1404-15-5 |
| Form | Solid |
| Storage | Powder -20°C |
[2] L D Williams, et al. Proc Natl Acad Sci U S A. Structure of nogalamycin bound to a DNA hexamer
[3] M Egli, et al. Biochemistry. DNA-nogalamycin interactions
[4] L H Li, et al. Pharmacol Ther. The biochemical pharmacology of nogalamycin and its derivatives
[5] P F Wiley, et al. J Am Chem Soc. Structure of nogalamycin
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